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Original Research

1. In silico approach towards the identification of potential inhibitors from Curcuma amada Roxb against H. pylori: ADMET screening and molecular docking studies
G Divyashri* ORCID, T P Krishna Murthy, Subramaniam Sundareshan, Pavan Kamath, Manikanta Murahari*, G R Saraswathy, Bindu Sadanandan
BioImpacts. 2021;11(2): 119-127. doi: 10.34172/bi.2021.19
PMCID: PMC8022237     PMID: 33842282     Scopus ID: 85106557158    
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Novel inhibitors from Mango ginger were identified against five drug targets of H. pylori. In silico potential of Mango ginger compound, gentisic acid with the drug target, shikimate kinase was evaluated. Results were found promising without any limitations.
Original Research

2. Molecular docking, molecular dynamics simulation, and ADMET analysis of levamisole derivatives against the SARS-CoV-2 main protease (MPro)

Khalil EL Khatabi ORCID, Ilham Aanouz, Marwa Alaqarbeh, Mohammed Aziz Ajana, Tahar Lakhlifi, Mohammed Bouachrine* ORCID
BioImpacts. 2022;12(2): 107-113. doi: 10.34172/bi.2021.22143
PMCID: PMC8905587     PMID: 35411302     Scopus ID: 85127183196    
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Molecular docking was performed to explore the binding affinity of the 12 selected molecules in the target enzyme and then evaluated for in silico ADMET properties. The best hits were subjected to molecular dynamics simulation.
Original Research

3. Multi spectroscopic and molecular simulation studies of propyl acridone binding to calf thymus DNA in the presence of electromagnetic force

Atena Sharifi-Rad ORCID, Zeinab Amiri-Tehranizadeh, Atiye Talebi, Niknaz Nosrati, Morvarid Medalian, Mahtab Pejhan, Nazanin Hamzkanloo, Mohammad Reza Saberi, Parisa Mokaberi, Jamshidkhan Chamani* ORCID
Bioimpacts. 2023;13(1): 5-16. doi: 10.34172/bi.2022.23592
PMCID: PMC9923809     PMID: 36817002     Scopus ID: 85152114849    
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The MD simulation and spectroscopic studies of the interaction of ct-DNA and propyl acridone revealed that a transition from the extended nucleic double helix towards the denatured structure.

As a peer-reviewed international open-access journal, BioImpacts publishes articles on basic and translational aspects of pharmaceutical and biomedical sciences. 
Acceptance rate: 24% 
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